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RT5B

TripleCore

LY3437943 Research Peptide (Lyophilized)

5mg

LY3437943 is a synthetic 39-residue peptide supplied as lyophilized material for laboratory research purposes only. In the published scientific literature this compound has been investigated as a concurrent agonist at the GIP receptor, the GLP-1 receptor, and the glucagon receptor. This material is intended strictly for laboratory research. It is not approved for human or veterinary use and is not a drug, food, supplement, or cosmetic.

Per vial

$32.00

5 mg $6.40/mg

Ships as a sealed box of 10 vials.

$320.00 per box.

Category / notes
GLP-1 / GIP / Glucagon – triple agonist
Available concentrations

Documents

Certificates of analysis are the supplier's test results for a lot. They are a reference point for your own incoming inspection, not a release decision, and not a statement that this material is safe to administer. What a COA does and does not tell you

Certificate of analysis

5mgOn request 10mgOn request 15mgOn request 20mgOn request 30mgOn request 40mgOn request 50mgOn request 60mgOn request

Safety data sheet

All strengthsOn request

Product data sheet

Lyotide Scientific · Wholesale supply

Research use only

RT5 GLP-1 / GIP / Glucagon – triple agonist Class B

TripleCore

5mg × 10 vials

01 Identity

Catalog / SKURT5
Product nameTripleCore
CategoryGLP-1 / GIP / Glucagon – triple agonist
Strength5mg per vial
PackBox of 10 vials
AppearanceLyophilized material in sealed glass vials
Supply10 unlabeled vials per box
ClassB

02 Commercial

Price / box $320.00
Price / vial$32.00
Minimum order1 box
PackagingUnlabeled vials, neutral tray

03 Handling

StorageStore lyophilized vials dry and protected from light; follow your lab SOP for temperature.
FormLyophilized powder in sealed, unlabeled vials
Intended useResearch use only — not for human or veterinary use

04 Documentation

Certificate of analysis Issued with the shipment for the lot you receive
Buyer testing A supplier COA is a starting point, not a release. Analytical reality
Labeling You label and test under your own name. Unlabeled supply

05 Conditions

Products are for research use only. Not for human or veterinary use. The buyer accepts sole responsibility for labeling, testing, and any claim made about the material after it leaves our warehouse.

Specifications

Catalog / SKURT5
Research identifierLY3437943
Also referenced in literature asretatrutide
FormLyophilized powder in sealed glass vials
Strength options5mg · 10mg · 15mg · 20mg · 30mg · 40mg · 50mg · 60mg
Packaging10 unlabeled vials per box
Intended useLaboratory research only — not for human or veterinary use
DocumentationCertificate of analysis supplied with each lot (identity and purity reference only; not a release decision)

Molecular and receptor profile

LY3437943 is a synthetic single-chain peptide of 39 residues. In the published literature it is described as a concurrent agonist at three receptors: the glucose-dependent insulinotropic polypeptide (GIP) receptor, the glucagon-like peptide-1 (GLP-1) receptor, and the glucagon receptor. That receptor set is why the literature classes it as a triple-hormone receptor agonist, and it is what separates it from the single-receptor GLP-1 analogues and from the dual GIP/GLP-1 receptor class. GIP and GLP-1 are the two incretin hormones; glucagon is not an incretin, and the three-receptor description above is the accurate one.

The compound is also referred to in the published literature as retatrutide. That name appears on this page only so a reader can match the material to the primary sources cited below; the research code is the identifier used throughout.

It is supplied here as lyophilized material in sealed, unlabeled vials for laboratory research. It is an investigational compound. It is not an approved medicine in the United States or anywhere else, and nothing on this page describes a use in humans or animals.

ModalitySynthetic peptide, single chain
Chain length39 residues
Receptor targetsGIP receptor · GLP-1 receptor · Glucagon receptor
CAS numberReported on the certificate of analysis
Molecular formulaReported on the certificate of analysis
Molecular massReported on the certificate of analysis

Packaging and supply format

Each box holds 10 sealed glass vials of lyophilized material in a neutral tray. The vials carry no label of any kind: no compound name, no strength, no lot number. The receiving laboratory identifies the material against the lot certificate of analysis and labels it under its own name and its own quality system. No labelling service is offered at any price.

Material is sold to businesses only and ships within the United States. Why the vials arrive unlabeled · Wholesale supply of unlabeled research peptides

What the certificate of analysis covers, and what it does not

The certificate that ships with a lot reports what the supplier's instrument measured on the supplier's sample: typically identity by mass spectrometry and purity by HPLC as a percentage of peak area. It is a reference point for the receiving laboratory's own incoming inspection.

It is not a release decision, and it is not a statement that the material is safe for any purpose. A standard peptide certificate routinely omits endotoxin, heavy metals, residual solvents and water content, and it says nothing about how the material was handled after the sample was drawn. What a COA does and does not tell you · Evaluating a certificate of analysis

Selected published literature

Peer-reviewed work on this compound, listed so a researcher can read the primary sources. These papers describe the compound as studied by others. They are not claims about the material sold here, and nothing in them describes a use for it.

  1. Coskun T, et al. LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept Cell Metabolism, 2022
  2. Jastreboff AM, et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial New England Journal of Medicine, 2023
  3. Rosenstock J, et al. Retatrutide (LY3437943), a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial The Lancet, 2023

Questions

What is LY3437943?

A synthetic 39-residue peptide investigated in the published literature as a concurrent agonist at the GIP, GLP-1 and glucagon receptors. It is an investigational compound and is not an approved medicine. It is supplied here as lyophilized material for laboratory research only.

Is this material intended for use in humans?

No. It is sold strictly for laboratory research use. It is not a drug, food, supplement or cosmetic, it has not been evaluated by the FDA, and any use in humans or animals is prohibited.

Do you sell to individuals?

No. Material is sold to businesses only, and ordering requires an approved wholesale account. Every visitor passes an attestation confirming they are buying as a business before an order can be placed.

What documentation ships with the material?

A certificate of analysis for the lot you receive. It reports what the supplier's instrument measured on their sample -- identity and purity -- and is a reference for your own incoming inspection, not a release decision and not a statement about safety.

What exactly arrives in a box?

Ten sealed glass vials of lyophilized material in a neutral tray, with no labels on the vials. The strength per vial and the total per box are listed in the data sheet above.

How should it be stored?

As lyophilized material, keep vials dry, sealed and protected from light, and follow your own laboratory's temperature SOP. Storage terms for this SKU are in the Handling section of the data sheet.

Do you ship internationally?

No. Orders ship within the United States only, including US territories and military addresses.